POLYNUCLEOTIDES
A new generation of skin treatments. Polynucleotides are designed to support the skin’s natural renewal processes, helping to improve skin quality, hydration and overall appearance.
What are Polynucleotides?
How Do They Work?
Key Benefits
Polynucleotides are injectable bio-stimulators derived from DNA fractions. They are used in aesthetic medicine to support skin quality, with research suggesting potential effects on fibroblast activity, hydration and the extracellular environment of the skin.
Once injected, polynucleotides are thought to interact with cellular pathways involved in tissue repair and remodelling. This may support processes associated with collagen and elastin production, contributing to gradual changes in skin structure and quality over time.
• Encourages the skin’s natural renewal processes
• Helps improve the appearance of firmness and elasticity
• Softens the appearance of dark circles and fine lines
• Promotes smoother, healthier-looking skin
THE EXPERIENCE
The Procedure & Downtime
The procedure involves targeted micro-injections into the skin. A session typically lasts 40 minutes. Downtime is minimal; you may see slight swelling or small papules at the injection sites, which usually resolve within 24 to 48 hours as the product integrates.
Critical Aftercare
• Gently cleanse the area and avoid touching for 6 hours
• Avoid makeup for 12 hours post-treatment
• Skip strenuous exercise and heat treatments for 24-48 hours
• Protect your skin with a high-quality SPF daily

Who are they for?
Results
Longevity
Polynucleotides are perfect for those seeking to treat specific aging concerns like crepey skin, under-eye hollowing, or scarring. They are suitable for all skin types looking for long-term health and repair.
As a novel treatment, results develop gradually. You will notice improvements in skin quality after 4 weeks, with peak results showing after a course of 3 treatments spaced 3 weeks apart.
The benefits of polynucleotides can last from 6 to 12 months. Maintenance sessions every 6 months are encouraged to sustain the positive effects and keep the skin resilient.

Treatment Areas
• Full face (fine lines, skin texture, and general repair)
• Periorbital zone (under-eye dark circles and wrinkles)
• Neck and Décolletage
• Back of hands and wider body areas
Premium Brands
At Skin Solutions, we use only the most clinically proven polynucleotide brands, such as Nucleadyn (Ameela), Plenhyage XL, and Vitaran, to ensure patient safety and good clinical outcomes.
Book your Polynucleotide Consultation
New Street, Henley-on-Thames, RG9 2BP
PHONE
+44 (0) 1491 522 106
enquiries@skinsolutionshenley.com
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Monday – Friday |
09:30 AM – 08:00 PM |
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Saturday |
10:00 AM – 07:00 PM |
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Sunday |
By Appointment Only |

